Filippo Castiglione

C-IMMSIM

A document describing the major features of the model can be downloaded here: description-by-examples.pdf

A description of the parameters used by the simulator is available here

C-ImmSim is on OMICtools, an innovative platform designed to assist life scientists identify the right bioinformatics tools.

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C-ImmSim

Simulation of the Immune System

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Filippo Castiglione, f [dot] castiglione [at] iac [dot] cnr [dot] it, is the main author.

Massimo Bernaschi, m.bernaschi [at] iac.cnr.it, did the optimization and

supervised the implementation of the parallel code. Few of other people sent bug reports, and very helpful feedback.

C-ImmSim is the C porting of IMMSIM, the IMMUNE SYSTEM SIMULATOR

originally developed by P.E. Seiden and F. Celada. (1991).

F. Castiglione developed the first version (1995) and afterwards with M. Bernaschi developed a parallel version.

C-ImmSim has now evolved to take into account other features not included in the original work of P. Seiden and F. Celada. In particular, since the first version, the model has been enriched to simulate HIV infection, hypersensitivity reactions, cancer immunotherapy, inflammation and type 2 diabetes.

For questions regarding code availability or collaborarion write to f [dot] castiglione [at] iac [dot] cnr [dot] it